Xarelto why evening meal

To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. The 2. The 15 and 20 mg tablets should be taken with food.

Also, take this medicine at the same time each day. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine.

Published 17 July Brexit Check what you need to do. Explore the topic Alerts and recalls. Is this page useful? Maybe Yes this page is useful No this page is not useful. Thank you for your feedback. Report a problem with this page. What were you doing? A joint PK model was used to estimate the bioavailability of rivaroxaban administered with a morning meal DVT data to rivaroxaban administered with an evening meal AF data. Regarding the impact of meal type on rivaroxaban, researchers analyzed previously published food-effect studies that compared a standard high-calorie, high-fat breakfast based on the Guidance for Industry , a high-carbohydrate breakfast, or applesauce with a low-calorie liquid meal.

After comparing steady-state exposures and predicted PK parameters with those seen in the DVT and AF studies, study authors concluded that the timing morning vs.

Conclusions: Evening intake of rivaroxaban leads to prolonged exposure to rivaroxaban concentrations and better matches the morning hypofibrinolysis. These results might help to further improve the efficacy and safety of rivaroxaban treatment.